Exploring the Anticancer Potential of Herbal Medicine in Prostate Cancer Treatment: Focus on Inula v
Investigating the Antiproliferative and Apoptotic Effects of Inula viscosa and Rubus caesius on Prostate Cancer Cells

By CMI HOSPITAL 29 Jun 2024, 14:52:34 WIB Kesehatan

The effects of herbal medicine on prostate cancer cells, one of the most common types of cancer and the second leading cause of cancer-related deaths worldwide. This study focused on seven medicinal plants: Viscum album, Inula viscosa, Hypericum perforatum, Lysimachia nummularia, Oleocanthal, Pinus pinaster, and Rubus caesius. Research was conducted on Du145 prostate cancer cells and mesenchymal cells derived from human adipose tissue to assess the potential anticancer effects of each plant at various doses.

The results showed that Inula viscosa and Rubus caesius had higher enhancing effects compared to the other medicinal plants. These two plants were non-toxic to mesenchymal cells derived from human adipose tissue and demonstrated the ability to inhibit cell proliferation and induce apoptosis in prostate cancer cells. Measurements were taken using the MTT method to determine cytotoxicity levels (IC50) and immunocytochemistry procedures to assess oxidative stress (eNOS), angiogenesis (VEGF), and apoptosis using the TUNEL method.

This study's findings indicate that Inula viscosa and Rubus caesius have potential as agents in prostate cancer treatment. These plants not only showed significant antiproliferative activity but also did not cause toxicity to mesenchymal cells from adipose tissue, suggesting their potential safety and effectiveness in prostate cancer therapy. This research paves the way for the use of medicinal plants as an alternative or adjunct in prostate cancer treatment.

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Source: https://www.mdpi.com/ (The Effect of Herbal Medicine on Prostate Cancer Cells in Culture)

Cancer treatment at CMI Hospital is based on complementary medicine aimed at repairing cell damage caused by cancer. Thousands of patients have successfully avoided surgery, chemotherapy, and radiation after undergoing this non-surgical cancer healing method. CMI Hospital remains committed to helping cancer patients.

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